Beyond CRT: LBBAP and the New Era of Physiological Pacing — Promise and Pitfalls: EP Edge Newsletter October 2025 Issue 5
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About this listen
In this episode of EP Edge Podcast, Dr. Niraj Sharma dives deep into the clinical promise and procedural realities of LBBAP:
- Clinical advantages: improved LVEF, narrower QRS, lower VT/VF and AF incidence.
- RV protection: reduced risk of pacing-induced cardiomyopathy.
- Sex-specific outcomes: women with NICM + LBBB derive greater benefit.
- Complications: lead fracture, TR progression, microperforations, and capture failure.
- Future directions: integrating imaging, refining technique, and advancing lead technology
This is where physiology meets precision—and where CRT is being redefined.
For: Source data/infographics see EPEDGE Newsletter on LinkedIn
For feedback, collaborations, or questions, email Dr. Niraj Sharma at epedgecast@gmail.com or connect on LinkedIn
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