Parenting a child who’s struggling with mysterious symptoms can be frightening and exhausting. You bring them to the doctor, the tests come back “normal,” and yet you know something isn’t right. You’re not imagining it—it’s real, and you’re not alone.

In this episode, Dr. Bill Rawls explains why Lyme disease testing often misses active infections, what it means for your child, and practical steps parents can take to advocate for accurate diagnosis and care.

Why does my child keep testing negative for Lyme disease even when symptoms persist?

• False negatives are common: Many Lyme disease tests, like the ELISA (enzyme linked immunoassay) or Western blot, rely on antibodies that may not appear early or consistently.
• Early infection can be invisible: During the initial infection or early Lyme disease, the immune system may not have produced enough detectable antibodies for serologic testing.
• Co-infections complicate results: Other tick-borne illnesses can mask or mimic Lyme disease symptoms, making accurate diagnosis even harder.
• Persistent or chronic infections: Sometimes, persistent infection or chronic Lyme can continue even after a negative test. Clinical findings, medical history, and physical examination help guide your provider toward the right diagnosis of Lyme disease.

It’s not bad parenting—it’s a dysregulated system of testing, not a failure of your vigilance.

Even when bloodwork looks clear, your child may still have an active infection. Understanding test limitations helps reduce frustration and empowers you to take action.

How can I tell if Lyme disease is being missed in my child?

• Watch for persistent, nonspecific symptoms: Fatigue, joint pain, headaches, or cognitive changes can appear long before tests turn positive.
• Consider medical history and exposure: Tick bites, outdoor activities, or living in endemic areas provide important clues.
• Use clinical judgment alongside lab tests: A single blood test rarely tells the full story; doctors often need multiple tests and examinations.

You don’t have to wait for a positive blood test to validate your child’s suffering.

Ready to help your child calm down quickly and regain control? Start using Quick Calm today and discover simple, science-backed strategies to regulate their nervous system.

What are the limitations of standard Lyme disease testing?

• ELISA and Western blot tests measure antibodies, not bacteria directly: If your child’s immune system hasn’t produced detectable antibodies, the test can look clear.
• False positives and delayed diagnosis are common: Inaccurate results can delay treatment, allowing Lyme bacteria to persist and cause chronic symptoms.
• Tests vary in performance: Different labs, methods, and timing of testing affect results.

Let’s calm the brain first—then focus on gathering the right information without panic.

Want to stay calm when your child pushes every button?

Become a Dysregulation Insider VIP and get the FREE Regulation Rescue Kit—your step-by-step guide to stop oppositional behaviors without yelling or giving in.

Go to www.drroseann.com/newsletter and grab your kit today.

What should parents do if Lyme disease tests come back negative?

• Keep a detailed symptom log: Track fatigue, joint pain, rashes, and cognitive...