Our medical rewrite today will be for 28 Days. The deep dive will be about medical management of alcohol use disorder.

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References used in this episode

Mechanisms of medications used for alcohol use disorder https://pubmed.ncbi.nlm.nih.gov/35133639/

LiverTox of disulfiram https://www.ncbi.nlm.nih.gov/books/NBK548103/

COMBINE study comparing naltrexone vs. acamprosate and medication management vs. cognitive behavior intervention https://pubmed.ncbi.nlm.nih.gov/16670409/

Meta-analysis of naltrexone and acamprosate for alcohol use disorder https://pubmed.ncbi.nlm.nih.gov/24825644/

Meta-analysis of long-acting naltrexone injection vs placebo https://pubmed.ncbi.nlm.nih.gov/34033183/

CYP2D6 Overview https://www.ncbi.nlm.nih.gov/books/NBK574601/

Hydrocodone pain control in CYP2D6 slow metabolizers https://pubmed.ncbi.nlm.nih.gov/34423496/

Systematic review of naltrexone efficacy in women with alcohol use disorder https://pubmed.ncbi.nlm.nih.gov/28247556/

Sex differences and opioid use https://pubmed.ncbi.nlm.nih.gov/24508560/

Review on sex/hormone differences and opioid effects https://pubmed.ncbi.nlm.nih.gov/34995646/

Acamprosate efficacy based on sex https://pubmed.ncbi.nlm.nih.gov/21895717/