2026 Seasonal Influenza Update with Dr. Joe Holley cover art

2026 Seasonal Influenza Update with Dr. Joe Holley

2026 Seasonal Influenza Update with Dr. Joe Holley

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 We delve into the recent surge of Influenza cases across large swaths of the United States in recent weeks. This year is shaping up to be a particularly difficult year for health care facilities and the patients who need them for treatment. Dr. Joe Holley joins us today to discuss what he’s seeing in the Memphis, Tennessee area and what the national flu outlook is. The most common Influenza A strain right now is causing a surge in ER visits and hospital admissions across the U.S. right now. The dominant Influenza A strain for the 2025-2026 flu season is the A(H3N2) subclade K, a variant with notable mutations. The annual vaccine is moderately effective at preventing severe illness and hospitalization and the subclade K variant responds well to antivirals such as Tamiflu. The episode was co-hosted by Sam Bradley and Jamie Davis. Scroll down for Podcast Discussion Summary Thank you as always to Paragon Medical Education Group for their long-term support of the Disaster Podcast. Dr. Joe Holley and the team at Paragon continue to provide excellent and customized disaster response training to jurisdictions around the U.S. and internationally as well. Podcast Discussion Summary Flu Trends and Vaccination Impact Joe and Jamie discussed the recent surge in flu cases, particularly affecting unvaccinated individuals and those with underlying health conditions. Jamie shared his experience of being admitted to the ER with influenza A and noted that vaccinated individuals were more likely to be discharged. Joe confirmed that national trends showed higher hospitalization rates and deaths among the unvaccinated, elderly, and those with other medical issues. Flu Awareness for Healthcare Jamie shared his severe flu experience, which included a high fever, chills, and muscle cramps, leading him to seek emergency care. He emphasized the importance of flu awareness for healthcare professionals, noting the recent increase in flu-related deaths and pediatric deaths reported by the CDC. Healthcare Virus Transmission Prevention Jamie and Joe discussed protective measures for healthcare providers against virus transmission, emphasizing hand hygiene, respiratory protection, and avoiding confined spaces with sick individuals. Joe highlighted the risk of virus spread in confined environments like airplanes, while Jamie shared personal experiences and encouraged listeners to take transmission prevention seriously, noting its impact on their community. Post-COVID Brain Fog Symptoms Jamie described experiencing “brain fog” after recovering from COVID-19, which made mental tasks difficult and required significant mental effort. Joe explained that this could be due to increased inflammatory markers and the body’s energy expenditure in fighting the infection. Sam noted that their household member who had not been vaccinated experienced different symptoms, and both Sam and their household member took about two weeks to regain their energy levels. Influenza Symptoms and Management Joe explained that vaccination can reduce the severity of symptoms, and both Jamie and Sam experienced typical symptoms of influenza A, with Jamie noting the importance of IV fluids in managing his symptoms. Sam described severe gastrointestinal symptoms, while Jamie mentioned being prescribed Zofran despite not experiencing nausea. Joe elaborated on how dehydration and inflammatory mediators contribute to symptoms, and rehydration can help alleviate them. Winter Virus and Flu Updates Jamie shared his experience of being delayed for release from the hospital due to low blood pressure, which was unusual for him. The medical team tried various methods to increase his blood pressure, including making him angry and having him walk around. Joe explained that while having the flu is unpleasant, it leads to the development of protective antibodies. Sam noted that the flu often overshadows other winter viruses, and Joe confirmed they are still seeing a variety of other respiratory infections. Early Flu Treatment and Testing Joe and Sam discussed the importance of seeking medical attention and testing for flu symptoms, with Joe recommending early treatment with antiviral drugs like Tamiflu, which are most effective within the first 48 hours of symptoms. Sam acknowledged that healthcare professionals might be reluctant to visit doctors when they need to, possibly due to a false sense of invincibility. Jamie emphasized the significance of early testing and treatment for flu, aligning with Joe’s advice. Influenza Testing and Treatment Discussion The group discussed influenza prevention and treatment, with Joe emphasizing the importance of early diagnosis and medication, particularly given the availability of over-the-counter rapid flu tests. Jamie noted that the COVID-19 pandemic had increased access to home testing, which Sam and Joe hadn’t previously considered. They agreed that while many people might choose to tough it out, getting tested early could be ...
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