今日代谢学最高分文献 - 2025-10-29

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今日代谢学最高分文献 - 2025-10-29

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科研喵使用AI读文献，祝你效率百倍，访问labcat.com.cn下载。本期关注发表在《Cellular & molecular biology letters》(影响因子9.2)上的重要论文"Cellular and molecular mechanisms underlying cardiovascular aging"。这项研究揭示了衰老如何通过基因组不稳定性、端粒缩短和蛋白质稳态丧失等机制，成为心血管疾病的主要风险因素。研究发现，细胞衰老、炎症反应、线粒体功能障碍和代谢紊乱共同加速了心力衰竭、心律失常和动脉粥样硬化等疾病的发展。更令人振奋的是，研究提出了一系列有前景的干预策略，包括代谢调节剂、衰老细胞清除剂和天然生物活性化合物，为延缓心血管衰老提供了新思路，有望减轻全球日益增长的心血管疾病负担。

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