今日代谢学最高分文献 - 2025-10-28

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今日代谢学最高分文献 - 2025-10-28

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科研喵使用ai读文献，祝你效率百倍，访问labcat.com.cn下载。本期关注发表在《Analytical chemistry》(IF: 6.7)上的重要研究"Aerith: Visualization and Annotation of Isotopic Enrichment Patterns of Peptides and Metabolites with Stable Isotope Labeling from Proteomics and Metabolomics"。由俄克拉荷马大学团队开发的Aerith软件包，解决了稳定同位素探针(SIP)研究中的一大难题——准确模拟和可视化部分标记的肽和代谢物的同位素模式。该研究创新性地结合了卷积算法、蒙特卡洛模拟和FFT算法，显著提高了同位素包络的计算效率，使研究人员能够精确解析葡萄糖、青霉素和微生物肽的复杂同位素结构。这一突破性工具将极大推动蛋白质组学和代谢组学中同位素标记研究的精确性和效率，为代谢通路研究提供更可靠的解析方法。

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