After a serious case of school bullying becomes too much to bear, sisters July and September move across the country with their mother to a long-abandoned family home. In their new and unsettling surroundings, July finds that the deep bond she has always had with September - a closeness that not even their mother is allowed to penetrate - is starting to change in ways she cannot entirely understand. Inside the house the tension among the three women builds, while outside the sisters meet a boy who tests the limits of their shared experiences. 

As a child Gifty would ask her parents to tell the story of their journey from Ghana to Alabama, seeking escape in myths of heroism and romance. When her father and brother succumb to the hard reality of immigrant life in the American South, their family of four becomes two - and the life Gifty dreamed of slips away. Years later, desperate to understand the opioid addiction that destroyed her brother's life, she turns to science for answers. But when her mother comes to stay, Gifty soon learns that the roots of their tangled traumas reach farther than she ever thought. 

It is 1909 in Spokane, Washington. The Dolan brothers live by their wits, jumping freight trains and lining up for day work at crooked job agencies. While 16-year-old Rye yearns for a steady job and a home, his dashing older brother, Gig, dreams of a better world, fighting alongside other union men for fair pay and decent treatment. When Rye finds himself drawn to suffragette Elizabeth Gurley Flynn, her passion sweeps him into the world of protest and dirty business. But a storm is coming, threatening to overwhelm them all.... 

Giovanna’s pretty face is changing, turning ugly, at least so her father thinks. Giovanna, he says, is looking more like her Aunt Vittoria every day. But can it be true? Is she really changing? Will she turn out like her despised Aunt Vittoria, a woman she hardly knows but whom her mother and father have spent their whole lives avoiding and deriding? There must be a mirror somewhere in which she can see herself as she truly is. 

Lil and Frank married young, launched into courtship when they bonded over how they both - suddenly, tragically - lost a parent when they were children. Over time, their marriage grew and strengthened, with each still wishing for so much more understanding of the parents they’d lost prematurely. Now, after many years in Boston, they have retired in North Carolina. There, Lil, determined to leave a history for their children, sifts through letters and notes and diary entries - perhaps revealing more secrets than Frank wants their children to know.

In the final year of the 19th century, Peter Winceworth has reached the letter S, toiling away for the much-anticipated and multi-volume Swansby’s New Encyclopaedic Dictionary. Overwhelmed at his desk and increasingly uneasy that his colleagues are attempting to corral language and regiment facts, Winceworth feels compelled to assert some sense of individual purpose and exercise artistic freedom, so he begins inserting unauthorised, fictitious entries into the dictionary.

Surging out of the sea, the Bass Rock has for centuries watched over the lives that pass under its shadow on the Scottish mainland. And across the centuries the fates of three women are linked: to this place, to each other. In the early 1700s, Sarah, accused of being a witch, flees for her life. In the aftermath of the Second World War, Ruth navigates a new house, a new husband and the strange waters of the local community. Six decades later, the house stands empty. 

Kieran Elliott's life changed forever on the day a reckless mistake led to devastating consequences. The guilt that still haunts him resurfaces during a visit with his young family to the small coastal community he once called home. Kieran's parents are struggling in a town where fortunes are forged by the sea. Between them all is his absent brother, Finn. When a body is discovered on the beach, long-held secrets threaten to emerge. A sunken wreck, a missing girl and questions that have never washed away....

In March 1865, the long and bitter War between the States is winding down. Till now, 23-year-old Simon Boudlin has evaded military duty thanks to his slight stature, youthful appearance, and utter lack of compunction about bending the truth. But following a barroom brawl in Victoria, Texas, Simon finds himself conscripted, however belatedly, into the Confederate Army. Luckily his talent with a fiddle gets him a comparatively easy position in a regimental band.

Contemptuous of their parents, who pass their days in a stupor of liquor, drugs, and sex, the children feel neglected and suffocated at the same time. When a destructive storm descends on the summer estate, the group's ringleaders - including Eve, who narrates the story - decide to run away, leading the younger ones on a dangerous foray into the apocalyptic chaos outside. 

Retired publisher Susan Ryeland is living the good life. She is running a small hotel on a Greek island with her long-term boyfriend, Andreas. It should be everything she's always wanted - but is it? She's exhausted with the responsibilities of making everything work on an island where nothing ever does, and truth be told she's beginning to miss her old life in London.

The morning of January 12, 1888, was unusually mild, following a punishing cold spell. It was warm enough for the homesteaders of the Dakota Territory to venture out again and for their children to return to school without their heavy coats - leaving them unprepared when disaster struck. At the hour when most prairie schools were letting out for the day, a terrifying, fast-moving blizzard blew in without warning. Schoolteachers as young as 16 were suddenly faced with life-and-death decisions.

Scotland, 1912. Antonia McCulloch’s life hasn’t gone the way she planned. She and her husband, Malcolm, have drifted apart; her burgeoning art career came to nothing; and when she looks in the mirror, she sees disappointment. But at least she will always have Balmarra, her family’s grand Scottish estate, and its exquisite glass house, filled with exotic plants that can take her far away. When her estranged brother’s wife, Cicely Pick, arrives unannounced, with her young daughter and enough trunks to last the summer, Antonia is instantly suspicious. 

In the fall of 1918, 13-year-old German immigrant Pia Lange longs to be far from Philadelphia's overcrowded streets and slums, and from the anti-German sentiment that compelled her father to enlist in the US Army, hoping to prove his loyalty. But an even more urgent threat has arrived. Spanish influenza is spreading through the city. Soon, dead and dying are everywhere. With no food at home, Pia must venture out in search of supplies, leaving her infant twin brothers alone....   

The bonds of family are tested in the wake of a profound tragedy, providing a look at the darker side of our society. Night. Sleep. Death. The Stars. is a gripping examination of contemporary America through the prism of a family tragedy: when a powerful parent dies, each of his adult children reacts in startling and unexpected ways and his grieving widow in the most surprising way of all.