When the father she barely knew dies suddenly, midwife Eve Wilson decides she owes it to him to go to the funeral and meet her step-family in Red Sand. After disappointment and heartbreak in Sydney, Dr Callie Wilson doesn't hesitate to move home and spend some time with her grieving mother. Melbourne-based obstetrician Sienna Wilson can't understand why anyone would want to bury themselves in the outback, but when her hospital sends her north to research the medical mystery affecting women in Red Sand, it seems fate is intent on bringing the three sisters together. 

Burra District Hospital's maternity unit is under threat and will close for births unless a new obstetrician can be found. Midwife Noni Frost needs a miracle. A single mum, Noni lives with her young son, Harley, and her Aunt Win, a free spirit and the beating heart of Burra Guest House. Noni's world is disrupted when Iain McCloud and his pregnant teenage daughter Jacinta move into the guesthouse to await the birth of her baby. There's instant chemistry between Iain and Noni, although he has no plans to stay on in town. 

A year after a tragic accident changed her life forever, Tess Daley is in desperate need of a change. When she is offered a position with the Flying Doctor Service, she seizes the opportunity to make a fresh start. Yet once she arrives in remote Mica Ridge she feels like an outsider, unable to connect with her patients and unsure if she'll ever fit in with this outback community. Station owner Soretta Byrnes has grown to love the company and chaos that comes with living in a house filled with boarders.

After her teenage daughter, Mia, falls in with the wrong crowd, Dr Billie Green decides it's time to leave the city and return home to Far Western NSW. When an opportunity to pursue her childhood dream of joining the Flying Doctor Service comes along, she jumps at the chance. Flight Nurse Daphne Prince - who is thrilled to have another woman join the otherwise male crew - and their handsome new boss, Morgan Blake, instantly make her feel welcome.

Sienna Wilson is living her dream in the city - a rewarding obstetrics job in a leading hospital, an apartment with a view and handsome Sergeant McCabe on call whenever she needs him. The last thing she wants is a posting to a remote outback town to investigate a medical mystery. But on arrival in Spinifex, Sienna is brought to life in new and exciting ways. In a community riddled with secrets, she meets troubled young barmaid Maddy, and tough publican Alma, both with their troubles to hide.

It's been more than 10 years since Maddy Locke left Spinifex, the small outback town where she gave birth to her daughter, Bridget. Now she's back to prove she's got what it takes to run the medical centre and face the memories of that challenging time in her life. But everything's changed - the old pub is gone, her new colleagues aren't pleased to see her and it's drier and hotter than ever.

Jacinta McLeod met Dr Jonah Armstrong delirious with malaria, and, even then, she needed to fight off the urge to know more about this fascinating patient. When the chance came to follow him to the wilds of Papua New Guinea and into a dangerous medical mission up the Sepik River, she took it, despite Jonah’s absolute ‘no’! Jonah had already lost his baby sister in the unsafe world of PNG. Now headstrong Jacinta had arrived, and he had to keep her safe. Despite his efforts, very soon they were both held captive in the jungle with a death sentence over their heads.

For midwife Montana, finding out she was pregnant was the best moment of her life. But days later she was widowed. Nine months have passed, her daughter is born and Montana knows she needs a fresh start. Dr Andy Buchanan is building services at Lyrebird Lake Hospital, and he wants Montana for the new maternity unit. He can’t get the beautiful new mum out of his mind.

Peony flower farmer Clancy Parker was born and bred in the Australian high country. Small-town Bundilla is the only place she will ever truly belong, even if staying means remaining alone. The man she'd loved is long gone, and single men are as rare as a summer snowfall. As soon as he could, street artist Heath MacBride escaped his complicated family and traded mountain peaks for city concrete. Now a commission to paint a mural on Bundilla's water tower brings him home. 

Misty saved the life of Dr Ben Moore, but that brief, wonderful connection was just a memory. Misty the midwife shuts out her daydreams and sets off for a new life in Lyrebird Lake, where she meets the new locum...and looks into Ben’s sea blue eyes! Ben moved to Lyrebird Lake for a chance to start again. But he wasn’t doing well in the single-parent role. Can Misty and Ben find the connection that saved his life once? Is Misty is the perfect person to make Ben’s family complete?

PR executive Gabrielle Moreau knows she has an easy life, but when her business partner claims she lacks career passion, she takes ownership of a dilapidated pub in a tiny riverside settlement to prove she can be a success without falling back on her privilege. Eighteen months ago, Settlers Bridge stonemason Hayden Paech had it all: a job he loved, good mates and a close family. All he needed was the right woman to come along, and he was ready to settle down. But one poor choice stole that chance, and he'll never risk caring for anyone again.

Vera De Rossi no longer believes in love...and thanks to her ex-boyfriend­, she's also broke, jobless, and staring down the barrel of a court case that could land her in prison. Turning to her talent for baking, Vera opens a cafe in Hanrahan, a cozy tourist town in the foothills of the Snowy Mountains. Josh Cody, once Hanrahan's golden boy, escaped 16 years ago with gossip hard on his heels and a pregnant girlfriend in tow. Now he's back: a qualified veterinarian - and a single dad with a lot to prove

Midwife Kelsie Summers dreamed of her holiday on Europe's most luxurious train. On departure, she can't believe her ill-timing when she sees Dr Lucas Larimar on that platform in Venice. Lucas hates surprises. Offering his seat to the woman who jilted him 15 years before was bad, but leaving her with his meddling grandmother was a hundred times worse.

After losing a patient, Dr Fliss Knight returns to small town Woodlea and buys a run-down farm, her confidence and city career in tatters. She intends to live a solitary life and hopes that the slow country pace will help her heal. When Fliss meets the cowboy living in the bluestone stables across the garden, all her hopes for a quiet and peaceful life fade. Despite his reserve, Hewitt is impossible to ignore. As they work together to care for an abandoned dog and her puppies, they find themselves drawn to each other. 

Bush nurse Lara McIntyre and rural journalist Toby Paxton are thrust into the limelight when an accident puts the heart of their community in jeopardy. The small country town of Bridgefield can’t manage without their general store and post office, but Lara can’t stomach the idea of out-of-town buyers revamping it with no regard for what the residents want. She’s also unsure where Toby’s allegiances lie in this fight. Loyalties are put to the test as the locals attempt to save the shop, with personal agendas, old grudges and misunderstandings threatening their best efforts.