Magneto, the X-Men's oldest, deadliest foe, has taken over a top-secret government installation that houses the Sentinels, powerful mutant-hunting robots. The X-Men must fight to keep this deadly technology out of Magneto's hands. But the Acolytes, Magneto's fanatical mutant followers, stand between the X-Men and victory - a victory that’s quickly slipping away - for a more ruthless enemy, the US government, holds the X-Men responsible for the installation's takeover!

The X-Men and Spider-Man must work together to stop the destruction of the multiverse in an adventure through the past, present, and future. Dinosaurs, knights, gunslingers, World War II heroes, old friends turned enemies, and future versions of themselves await them on this incredible adventure.

The Avengers journey into deep space, where they unite the intergalactic races against the Builders - deadly aliens who seek to destroy the known galaxy. While the heroes are gone, Thanos sets his sights on Earth, sending the Black Order to launch the assault. It falls to the other heroes of Earth - the Inhumans, the Black Panther, Namor the Sub-Mariner, Doctor Strange, the X-Men, and more - to defend Attilan, Wakanda, Atlantis, and the rest of the planet. To defeat Thanos, the defending forces will need to deploy a new weapon - one that may be as deadly as the invading force.

While visiting Japan, Wolverine is recruited to recover a stolen experimental drug, one that has the potential to be a true miracle cure for all human disease - or a sadistic means of enslaving the world. With every hour bringing mankind closer to tragedy, he embarks on a daring mission to identify the thieves and thwart their terrifying agenda.

Born to a rarified breed of Russian aristocracy, Kraven the Hunter had stalked and killed every animal known to man and considered himself the world's best big-game hunter. It was this confidence that brought him to New York years ago, in an obsessive quest to hunt what he considered the city's greatest prey: Spider-Man. But his target eluded him time and again, mocking him at every turn.

The 26th century. Humanity has expanded beyond Earth’s system to hundreds of planets that colonists now call home. But the United Earth Government and the United Nations Space Command is struggling to control this vast empire. After exhausting all strategies to keep seething colonial insurrections from exploding into a full-blown interplanetary civil war, the UNSC has one last hope.

Doctor Stephen Strange, the Sorcerer Supreme, has defeated demonic hordes, battled evil wizards, and tirelessly defended our realm against invading interdimensional armies. But when a dangerous dream begins inspiring normal people to act out their darkest ambitions, even Doctor Strange is pushed to his very limits.

This exciting new anthology has over a dozen original tales starring the vicious foes of Marvel's superheroes: Greg Cox's chronicle of the Super-Skrull's conflict with the Avengers, Michael Jan Friendman's story of evil Loki's latest attempt to snare his stepbrother Thor, Adam-Troy Castro's tale of a mutant who brings Magneto and X-Men's Professor X together in a unique manner, Glenn Greenberg's pairing of Venom and the Absorbing Man in an unlikely jailbreak.

Peter Parker is caught in a complicated web. Working in a cutting-edge laboratory, he's a young scientist who's trying to make a difference. Yet he's constantly burdened by the responsibilities of his second career as the crime-fighting Spider-Man. Wilson Fisk - the so-called Kingpin of Crime - has returned to New York, establishing himself publicly as an altruistic entrepreneur and philanthropist. Spider-Man knows better, but he can't uncover Fisk's scheme, which, if executed, will make the crime lord too big to fail.

The alien shapeshifters called the Chitauri were defeated by the Ultimates in a decisive battle, but suspicious activity leads the Ultimates to believe that not all of the aliens were destroyed in that cataclysmic attack. Stark Industries has developed means of quickly and easily detecting Chitauri DNA, but the federal government refuses to adopt the technology, claiming that if the tech is widely available, the Chitauri will find a way to fool it. Frustrated by the government’s seeming unwillingness to protect its own people, Captain America takes matters into his own hands.

Centuries ago, a never-before-seen group of heroes gathered as the Avengers of their ancient era to fight the Zodiac, foes who wielded unimaginable arcane energies channeled through a mysterious Key. The resulting battle devastated vast swaths of the planet. The Key was lost, and the Zodiac went into hiding, influencing world events from the shadows, waiting for the stars to align to usher in their return. When strange beings exhibiting the traits of the 12 astrological signs appear in the 21st century, the Avengers again answer the call to assemble.

The fate of the entire Marvel Universe hangs in the balance as Earth's mightiest heroes face their greatest challenge! Summoned across the stars by the mysterious and unbelievably powerful Beyonder, the Avengers, Spider-Man, the Fantastic Four, and the X-Men are set against their deadliest foes on the mysterious planet known as Battleworld - with the winner promised the ultimate prize. But as battle lines are drawn, new alliances are forged, and old enemies clash, one among them is not willing to settle for anything less than godhood.

When a baddie drops out of a sky-high window (Did he jump - heh heh - or was he pushed?), Daily Bugle publisher J. Jonah Jameson wants Spider-Man to take the rap. Has the wall-crawler come to the end of his rope? Does his life hang by a slender thread? To swing clear of this one, he's got to snoop on an international oil conference. There's blackmail! Radioactivity! And a welcoming committee of death-dealing arch-villains!

In a Manhattan warehouse, an innocent man has been murdered during a mysterious crime. Evidence points to the involvement of Venom - the alien symbiote obsessed with Spider-Man's destruction. Yet Venom has always safeguarded innocent lives. Has Venom gone completely around the bend, or is there another suspect? Spider-Man thinks there is more to the crime than meets the eye. The specter of the Hobgoblin, one of Spider-Man's nastiest foes, falls on a series of thefts and leads the web-slinger to a deadly secret that may cause New York's destruction.

Piloting a shuttle through a deadly solar flare, Jean Grey saves the X-Men, but is possessed by one of the universe's most powerful forces - the Phoenix. As she adapts to her new powers, the mutant team launches an assault against the clandestine organization known as the Hellfire Club. Once inside, however, Jean is tricked by the villain Mastermind into betraying her teammates. She becomes first the Hellfire Club's Black Queen and then Dark Phoenix, as the power to destroy worlds bursts forth uncontrolled.