When Danni Carter moves to Cornwall from London, she hopes it will be the fresh start she so desperately needs. She’s nervous, but hopefully the change of scene will help her to finally forget her feelings for Lucas Newman, a man she can never be with, because he’s already engaged to Danni’s best friend, Esther. But when Lucas and Esther decide to follow Danni to Cornwall, and both announce they will be working with her at the new St Piran’s hospital, Danni is thrown into turmoil again.

In the heart of Dressmakers' Alley, Madame Pauline’s sweatshop is rumoured to be a particularly unpleasant place to work. Filled with seamstresses paid a pittance who turn a blind eye to what darker activities are hidden behind locked doors. Young Winnie Brown is keen to prove her value to the Women Movement and secures a job as a seamstress to investigate the whispers of some unsavoury goings on. Her concerns are soon justified when she hears a desperate cry for help.

The three sisters of Victory Walk in East London will face heartache and tears on the home front. As rationing, blackouts and bombs start to bite, life will change forever for the three sisters.

Bristol 1936. Jenny Crawford has resigned herself to a loveless marriage living hand to mouth with their two children. Like many others, husband Roy struggles to find work at the docks but a chance encounter turns the family's fortunes around. Not only does he get regular work but they are also allocated a council house on Coronation Close on the outskirts of the city. Jenny and the children are overjoyed, this is the fresh start she could only ever dream of. But trouble feels never too far away.

Hampshire, 1913. Amidst the glitz and glamour of England’s High Society, Sarah Trenwith is more of a wallflower living in the shadow of her beautiful sister Marianne. But as the war approaches Sarah will have to step out of the place society and her family have assigned her if she’s to do her part and claim the love she always dreamed of from afar.

Pearl has given up on her dreams of being a journalist after being denied a promotion because of her gender. Joining the WAAF as a radio telephone operator for Bomber Command, Pearl's new job at RAF Fenthorpe serves two purposes – providing an income for her grandmother, and keeping a close eye on her younger sister, Thea, an instrument repairer at another Lincolnshire bomber station.

Lady Joanna Harcourt and her daughter, Sarah, discover their life of luxury at Goodwill House is over. Because with Lord Harcourt away fighting, the Harcourt girls are facing financial ruin. Lady Joanna is terrified of losing their home, but for Sarah, this means her dreams of becoming a doctor are over. Headstrong Sarah isn’t one to quit! War or not, she’s determined to find a way to save her home and follow her dreams - whatever it takes.

Autumn 1941, and as female conscription looms, three women arrive at the Bell Works Factory in Hucknall to work on the Spitfire production line. Lily soon realises her real dream is to pilot the planes; Edna longs to be reunited with her evacuee daughter, but soon discovers she has a much bigger problem; and Jeannie fears the worst after weeks of no news from her fiancé. Despite all the heartache, with a bit of festive cheer and 'can do' attitude, The Engine Girls will pull together and do all they can to ensure Britain's safe for the New Year.

It is 1937, and Alice, Edith and Marg continue to face hardships every day, growing up on one of the poorest streets in Blackpool. Penniless, their friendship has helped them survive this far, but it'll take more than that to see them through the dark days ahead. Alice is coping with a violent father. Marg is left reeling after a dark secret about her birth comes to light and threatens to destroy the life she knows, and Edith is fighting to protect her alcoholic mother from the shame of their neighbours and keep her brother on the straight and narrow. 

Cambridgeshire - March 1939. As the clouds of war begin to gather in Europe, the Talbot family of rural Blackberry Farm will be torn apart, just as so many families all over the world will be. Life will never be the same again. Whilst in London, the Salmons family will feel the pain of parting and loss. Brought together by war, the two families become intertwined and, as the outlook looks bleak, they must draw on each other’s strength to fight through the hard times.

It's 1957, and three young women are beginning their nursing training at the Florence Nightingale Hospital in London's East End. Winne desperately wants to win her mother's approval - but will following in her footsteps and becoming a nurse help? Tearaway Viv has never been one to follow the rules, though the Nightingale may help her mend her ways. Beth is following her late sister's dream by training as a nurse. Will it be the right path for her? There's a steep learning curve ahead. But with friendship on their side, the Nightingale Daughters are ready to rise to the challenge.

London, 1941. The Blitz. When a Royal Navy memo arrives at head office, requesting female recruits to sign up as motorcycle dispatch riders, delivering highly classified orders across the country, three women jump at the chance to sign up for the most dangerous jobs in London.

As war rages, Barbara Sinclair is desperate to escape her unhappy home life. And with the threat of German bombs ever present, Barbara reluctantly agrees to marry John, her childhood friend, who is leaving to join the RAF. But an encounter with Alex Everton, a dashing Spitfire pilot, complicates matters for Barbara. With emotions running high, she begins to question whether she has made a terrible mistake. With the constant threat of death all around her, Barbara must try to find a way to deal with the complexities of her difficult home life and her emotional relationships, too.

Midwife Ella Mehenick left the small Cornish town of Port Agnes for London and never looked back. But when her seemingly perfect life crashes down around her, there’s only one place she can heal her battered heart - the place she once called home. Ella is quickly welcomed into the small community midwife team and loves her new job caring for mums and their precious babies - it’s what she does best! But being back also means facing ex-flame Dan Ferguson...the first man to break her heart.

Following a humiliating experience involving the man she thought she’d marry, Iris Tredwick signs up to the Wrens in order to escape and - hopefully - find ‘the right sort’ of man to please her mother. After a bumpy start, Iris manages to befriend outspoken Mary and dreamer Sally as they are sent to their first posting - in Orkney. There she meets engineer Rob, whose flirtatious nature both charms and confounds straight-laced Iris. Much more appropriate for her is local doctor Stewart, if only she felt the same spark for him as she does for Rob.