Following a violent and messy divorce, young Maisie Farange floats back and forth between her parents, Beale and Ida, who use her as a weapon to torment each other in their ongoing, internecine war. Eventually the parents both remarry, and it becomes clear that the new spouses care more for Maisie than her own parents. Beale and Ida soon embark on a series of extramarital affairs, leaving Maisie in the care of the new step-parents, who begin their own affair with each other.

The Dean of Innuendo weaves a tale of a complex romantic quadrangle when a wealthy collector of objets d'arte and his daughter innocently marry a pair of lovers, the beautiful Charlotte and a charming Italian prince. Complications ensue.

Self-made American millionaire Christopher Newman arrives in Paris brimming with hope and optimism, excited to experience the culture and, hopefully, find the perfect woman to become his wife. After a chance encounter with American expatriate friends, his attention is drawn to Madame de Cintré, 25-year-old widowed daughter of the late Marquis de Bellegarde. Having fallen on hard times, the centuries-old aristocratic family permits Newman's courtship to proceed; however, they later persuade the widow to break off her engagement to the nouveau-riche businessman.

The interwoven relationships of a close circle of friends involved in the launching of two young ladies into society and marriage are examined through repartee.

Lambert Strether, a mild, middle-aged American of no particular achievements, is dispatched to Paris from the manufacturing empire of Woollett, Massachusetts. The mission conferred on him by his august patron, Mrs. Newsome, is to discover what, or who, is keeping her son Chad in the notorious city of pleasure and to bring him home. But Strether finds Chad transformed by the influence of a remarkable woman.