The year is 1855, and on the LNWR train to London, a criminal is being escorted to his appointment with the hangman. But the wily Jeremy Oxley, conman, thief and murderer, has one last ace up his sleeve: a beautiful and ruthless accomplice willing to do anything to save her lover, including committing cold-blooded murder... When Inspector Robert Colbeck learns that Oxley, his nemesis, has once again escaped, black memories of their shared past leave him no choice but to do his duty.

An exquisite silver coffee-pot in the shape of a locomotive is on its way to Cardiff in the care of silversmith, Hugh Kellow. When the coffee-pot is stolen and a murder is committed, Inspector Colbeck and Sergeant Leeming are called in to investigate.

When the engines finally met, there was a deafening clash and the Brighton Express twisted and buckled, tipping its carriages on to the other line. It was a scene of utter devastation. October 1854. As crowds of passengers rush to make the departure of the London to Brighton Express, a man watches from the shadows nearby, grimly satisfied as the train pulls out of the station. Chaos, fatalities and unbelievable destruction are the scene soon after when the train derails on the last leg of its journey.

Derby Day at Epsom Downs and a multitude of people crowd to watch the races: dukes and dustmen, bishops and beggars, privileged ladies and prostitutes. The gamut of Victorian society, though, is also a hotbed for crime and crooks of all kinds. With the country a-flutter in the run-up to this national occasion, events reach fever pitch when a disembodied head is discovered on a passenger train at Crewe; the first in a murky course of events that takes in murder, fraud and race-fixing.

The Railway Detective faces his most dangerous adversary yet. It is 1852, and Inspector Robert Colbeck and his assistant Sergeant Victor Leeming are faced with their most complex and difficult case to date. As a train speeds over the Sankey Viaduct, a man is hurled from a carriage and plummets into the canal below. It later transpires that he has been stabbed to death. With no papers by which to identify the man, the detectives' investigation is hampered from the start. Suspecting that the victim may have come from continental Europe, Colbeck and Leeming take the case to France where a new railway is being built by a British contractor.

1860, Wimborne, Dorset. Rebecca Tullidge, miserably married to her callous husband, is having an affair with a railway officer, John Bedloe. Much to her distress, she trips over her lover's dead body on the railway tracks. Determined to win votes for the upcoming election of mayor, Mr Feltham calls for Inspector Colbeck and Sergeant Lemming to solve the hideous crime, which takes longer than anticipated.

Following a string of successful performances along the west coast, the Moscardi Circus is travelling by train to Hexham on the Newcastle to Carlisle Railway for their next show. Yet a collision on the track causes pandemonium. When the headless body of a woman is discovered in nearby woodland, Inspector Colbeck is desperate to lend assistance, however a reluctant Superintendent Tallis forbids him from doing so. 

East Anglia, 1861. Alone in a first-class carriage, the Swarbricks are robbed at gunpoint. But when the universally admired Swarbrick fights back, the train robber takes more than money and jewellery, killing the man working to unify East Anglia's tangle of railway networks. Inspector Colbeck is brought in from London, but as Swarbrick's glowing reputation begins to crumble, the line of investigation isn't clear. 

London, 1851. With the opening of the Great Exhibition at hand, interest in mounting in the engineering triumphs of the railways, but not everyone feels like celebrating. In an audacious attack, the London to Birmingham mail train is robbed and derailed, causing many casualties. Planned with military precision, this crime proves a challenge to Detective Inspector Robert Colbeck who fights to untangle a web of murder, blackmail and destruction.

Halloween 1861. A special train with two carriages steams across the Lake District at night on its way to a place notorious for its record of supernatural incidents. Lighting inside the carriages is poor, and without warning, the lamp goes out in the last compartment of the second carriage, plunging it into darkness. When the special reaches the end of its journey, the passengers pour out on to the station platform. There are almost 60 of them in all, laughing and jostling. 

When Robert Pomeroy, a young undergraduate at Corpus Christi College, finds a letter slipped under his door in the early hours of a rainy day, he flies into a panic. He hurries to the railway station. But he doesn’t reach his destination alive. Inspector Colbeck and Sergeant Leeming are called upon to investigate this tragedy on the railway. It soon becomes apparent that Cambridge’s hopes of success in the forthcoming boat race rested on Pomeroy’s shoulders. 

December 1860. Headed for the morning shift at the Swindon Locomotive Works is an army of men pouring out of terraced houses built by the GWR, a miniature town and planned community that aims to provide for its employees from cradle to grave. Unfortunately, boilersmith Frank Rodman is headed for the grave sooner than he'd expected, or he will be once his missing head is found. Colbeck, the Railway Detective, finds his investigation into Rodman's murder mired in contradictions. 

November 1907. George Dillman and Genevieve Masefield sail from Liverpool to New York on the maiden voyage of the luxurious Mauretania. Employed by the Cunard Line again as private detectives, they pose as passengers on what proves to be a very eventful crossing. Dillman is instrumental in rescuing a crew member from being washed overboard in severe weather, but he is unable to save one of the first-class passengers from the same fate. 

Nicolas Picard is riding home from Exeter when he's attacked by a snarling wildcat. Yet, when the body is found, there are lacerations on his neck put there by a human hand. He is involved in a land dispute and his wife claims to be the benefactor on his behalf. Picard's mistress emerges to stake her claim then a third woman—wife of the deceased original owner of the land—comes forward. Ralph Delchard and Gervase Bret have three human wildcats trying to tear out each other's throats.

Ralph Delchard and Gervase Bret are royal commissioners appointed to investigate irregularities that come to light during the compilation of the Domesday Book in the reign of William the Conqueror. They arrive in Canterbury to be met by the news that the body of a young girl has been found, apparently killed by a poisonous snake. Their investigation takes them to the leper hospital in Harbledown where the girl used to take herbs. Once they establish that she was murdered by human agency, they begin to uncover all sorts of hidden secrets in the town....