Dani, Meg, and Charlotte have bonded over babies, barbeques, and backyards, but when they escape for a girls' weekend away, they can't bring themselves to return to lives that don't seem to fit anymore. All three of these women thought they would be different. None of them thought they'd be facing down 40 and still wondering when life starts. What they do when they realize where they're headed is both inspiring and wildly entertaining.

When Cara felt her teenaged children slipping away and saw an empty nest on the horizon, she decided the best way to fill that void was with dogs - lots of them - and so her foster journey began. In 2015, her Pennsylvania farm became a haven for Operation Paws for Homes. There were the nine puppies at once, which arrived with less than a day's notice; a heart-worm positive dog; a deeply traumatized stray pup from Iraq; and countless others who just needed a gentle touch and a warm place to sleep.

Alexis Gold knows how to put the "work" in working mom. It's the "mom" part that she's been struggling with lately. Since opening her own advertising agency three years ago, Alexis has all but given up on finding a good work/life balance. Instead, she's handed over the household reins to her supportive, loving partner, Tommy. While he's quick to say they divide and conquer, Alexis knows that Tommy does most of the heavy lifting - especially when it comes to their teenage daughter, CeCe. Their world changes in an instant when Tommy receives a terminal cancer diagnosis.

Attorney Olivia Sinclair is shocked when she receives an anonymous video showing her husband Richard sleeping with someone else. After years of handling other people’s divorces, she thought she could recognise a marriage in trouble. She angrily throws Richard out of the home they share. But days later she’s arrested - for the murder of his mistress. Olivia knows she’s innocent but, with all the evidence pointing at her and an obvious motive, she must find the real killer to clear her name. 

For years Greg Mahle struggled to keep the last of his family-run restaurants afloat in Ohio. When it finally closed, he was broke and unsure what to do next. Then a stranded vanload of puppies changed his life forever. Join journalist Peter Zheutlin as he travels with Greg from Ohio to the Gulf Coast on his Rescue Road Trips to bring hard-luck dogs from the Deep South to loving "forever families" up north, with the help of many selfless volunteers along the way.

For Tabitha, the day that changed everything started like any other. She woke up, leaving her husband, Andy, sleeping. Downstairs, she boiled the kettle and enjoyed a cup of tea as the sun rose. Upstairs, Andy’s alarm sounded and Tabitha took him a freshly brewed coffee, like every other morning. She called his name, she nudged his shoulder. But Andy wouldn’t wake up.  

Gemma didn’t expect her life to look like this. She’s still living with her mother, who steals her leggings and tells her off for leaving crumbs in the butter. After 20 failed interviews she thought she’d got her dream job as a journalist - except it turns out to be writing articles about cats that look like George Clooney. Luckily she has her wonderful boyfriend, Jack, to help her forget just how awful things are. Then Jack dumps her out of the blue. With nothing but her childhood teddy bear, Stanley, and a whole heap of heartbreak, Gemma resolves to turn things around.

When Thea sees her old family home is up for sale - a beautiful old rectory in the small town where she and her childhood sweetheart, now husband, Drew, grew up - she knows she has to have it. Her parents moved her away suddenly when she was 11, but her childhood there was filled with happy memories. Drew seems less sure, but Thea is certain it’s the perfect place to raise their two children. But as the last boxes are unpacked, Thea can’t seem to settle. She thought the move would bring her family closer together, but Drew is getting more distant by the day. 

From one of the most respected figures in the dog-rescue community come the harrowing, funny, and inspiring stories of nine incredible dogs that shaped her life. 

Me and Will. Will and Me. A perfect match. He said he would always be there for me, but it’s been a year since he drained his coffee, walked out the front door and vanished. Did he leave me? Or did something terrible happen? I’m scared someone finally found out about what happened on the drive home that night...I lie awake at night trawling the internet for rental properties, desperate for an escape. Until I see my husband’s gorgeous face smiling back at me from a photograph on the fireplace in someone else’s home, and something inside of me snaps....

79-year-old Gloria Frensham is a hoarder. She lives amongst piles of magazines, cardboard boxes and endless knickknacks that are stacked into every room of her home and teeter in piles along the landing and up the stairs. She hasn’t left the house in years, but when a sudden smell of burning signifies real danger, she is forced to make a sudden departure and leave behind her beloved possessions. Determined she’s not ready for a care home, Gloria sets out to discover what life still has to offer her.  

Annabel Ford has everything under control, devoting her time to her twin boys and keeping her household running smoothly. But when her husband of a decade announces that he's leaving, she's blindsided. And suddenly her world begins to unravel. Piper Whitley has always done her best to balance it all - raising her daughter, Fern, by herself while advancing her career as a crime reporter. Only now that she's finally met the man of her dreams, Fern's absentee father shows up, throwing everything into a tailspin.

Nina Garrity learned the hard way that her missing husband, Glen, had been leading a double life with another woman. But with Glen gone - presumably drowned while fishing on his boat - she couldn't confront him about the affair or find closure to the life he blew apart. Now, a year and a half later, Nina has found love again and hopes she can put her shattered world back together. Simon, a widower still grieving the death of his first wife, thinks he has found his dream girl in Nina, and his charm and affections help break through to a heart hardened by betrayal.

On the surface Sloane has the perfect life - an adoring husband, a precocious daughter, and enough financial security to be a stay-at-home mom. Still, she can't help but feel as though something - or someone - is missing.

Nate Beckett has spent his life fighting wildfires instead of the lies and rumors that drove him from his Colorado hometown. His mother begs him to come back now that his father has been released from prison, but it isn’t until he’s sidelined by an injury that he’s forced to return and face his past. But that means facing Brenna, too. Fourteen years ago, Nate was in love with the preacher’s daughter. When Pastor Strickland discovered Brenna defied him to sneak out with Nate, the fight between Strickland and Nate’s drunken dad was loud - and very public.