Bridget Collins is in dire straits - she needs to get out of New York, fast. With two young siblings under her wing, her options are limited. Her priest sends her as an outplacement agent on the orphan trains that run from New York to out west. With almost 40 orphans under her care, she's relieved that fellow and more experienced outplacement agent Carl Watson is there to guide her. But Carl is dealing with his own trauma and finds it difficult to handle the pain the orphans are dealing with.

Virginia, 1933: Lauren Greenwood was born to look pretty and land a rich husband. For her and her high-society family, it’s easy to forget that America is in the devastating grip of the Great Depression, where children run wild in the streets, endless queues for soup kitchens line sidewalks, and desperation hangs in the air. But when a young servant comes to Lauren, pregnant and begging for help, her world crumbles. Someone she loves is responsible, and when she finds out the shocking truth she must decide: Protect the Greenwood name or be cast out? 

Bristol 1936. Jenny Crawford has resigned herself to a loveless marriage living hand to mouth with their two children. Like many others, husband Roy struggles to find work at the docks but a chance encounter turns the family's fortunes around. Not only does he get regular work but they are also allocated a council house on Coronation Close on the outskirts of the city. Jenny and the children are overjoyed, this is the fresh start she could only ever dream of. But trouble feels never too far away.

As war looms in Europe, 18-year-old Jane Shaw runs the household as an unpaid servant on a meagre budget. When tragedy strikes and she loses her beloved younger brother in suspicious circumstances, Jane takes a position in service looking after Ned, a troubled young boy. Here she meets dashing David Heron, Ned's Uncle and they form an immediate attachment until she is dismissed after being accused of stealing a piece of jewellery. Returning home, Jane and her sister, Melia, are soon orphaned and left at the mercy of their Aunt Alice.

While war rages across the world, Kate struggles on her family farm by the wild Atlantic Ocean. But when she meets American airman Tony, whose blue eyes are as stormy as the sea, her life collides with the war in ways she never imagined.Their time is cut short when Tony leaves for war, promising to come back for her. Only then does Kate learn she is carrying his child - and when her family finds out, she is shunned and banished to a Magdalen Laundry to be imprisoned.