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Publisher's Summary

The book has information for patients and practitioners on optimizing mitochondrial function for greater health and longevity.

Why do we age? Why does cancer develop? What's the connection between heart failure and Alzheimer's disease or infertility and hearing loss? Can we extend lifespan, and if so, how? What is the exercise paradox? Why do antioxidant supplements sometimes do more harm than good? Many will be amazed to learn that all these questions, and many more, can be answered by a single point of discussion: mitochondria and bioenergetics.

In Mitochondria and the Future of Medicine, naturopathic doctor Lee Know tells the epic story of mitochondria - the widely misunderstood and often-overlooked powerhouses of our cells. The legendary saga began over two billion years ago, when one bacterium entered another without being digested, which would evolve to create the first mitochondrion. Since then, for life to exist beyond single-celled bacteria, it's the mitochondria that have been responsible for this life-giving energy. By understanding how our mitochondria work, in fact, it is possible to add years to our lives, and life to our years.

Current research, however, has revealed a dark side: many seemingly disconnected degenerative diseases have tangled roots in dysfunctional mitochondria. However, modern research has also endowed us with the knowledge on how to optimize its function, which is of critical importance to our health and longevity. 

Lee Know offers cutting-edge information on supplementation and lifestyle changes for mitochondrial optimization, such as CoQ10, D-Ribose, cannabinoids, and ketogenic dietary therapy and how to implement their use successfully. 

Mitochondria and the Future of Medicine is an invaluable resource for practitioners interested in mitochondrial medicine and the true roots of chronic illness and disease as well as anyone interested in optimizing their health.

PLEASE NOTE: When you purchase this title, the accompanying PDF will be available in your Audible Library along with the audio.

©2018 Lee Know (P)2019 Chelsea Green Publishing

What listeners say about Mitochondria and the Future of Medicine

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Amazing. Difficult subject to write and narrate - both done with aplomb.

I've started an experimental regimen of NMN (NAD+) and it was difficult to garner enough information on the how and why's. This book helped me understand so much about the systems that drive out bodies - as well as inadvertently helping me understand why the NAD+ cycle is such an interesting avenue into longevity and health.
I applaud the writer for taking such a technical topic and making the research so clear and easy to understand. I read/listen-to a lot of science and tech books and I'm very aware of the skill involved in doing these topics well for the average reader.
I don't write reviews often - but this one was a MUST.
The narrator needs a special shout-out - one thing to write in way that connects - a different (and just as challenging, I'd wager) task to find someone to read it in a way that's both engaging and portrays an understanding of the science and terminology.
Hats off to this entire production.
Exceptional book, exceptional narration, fascinating content.

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Mind blowing book

I'm not a physician, I'm a high school drop out who loves learning about the human body and health. I had to replay the first chapter literally 10 times just to truly grasp cell structure.

The information in this book is rich and the narrator was great. At first I thought his way of talking way a bit exaggerated but it grows on you and he keeps you engaged.

I love this book and I'll probably go through it again lol

EDIT: I've now repeated it 5 times and some chapters 10-15 times. This book is insane!

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Fascinating and informative

There's a lot to digest so I decided to listen a second time. Definitely time well spent for anyone who wants to increase their healthspan.
This is the only work I have read that has explained the Why? of why exercise and calorie restriction extend healthy life whereas excess/poor food and a sedentary lifestyle shorten healthspan.

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Unbelievable !

So much technical & common sense knowledge in here of immense value. I highly recommend if you're after learning.

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Awesome

Fantastic, well structured, well performed and informative journey into mitochondria. Sufficient detail without being mind boggling or dreary. 👍

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Amazing

Love this book. Can't wait to listen to it again. Contains fascinating information for a budding science buff.

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fascinating book

awesome book. so many things involved that i will listen to this more than 10 times. mitochondria is involved with everything

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An eye opener!!

This is paradigm shifting. Our doctors should be forced to read such cutting-edge research ...
Highly recommend for any health enthusiast.
*****

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  • Robert Robinson
  • 18-12-2019

Fascinating

Really loved this book. If you only read this comment and not the book, start taking coq10.

30 people found this helpful

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  • James Bruno
  • 14-02-2020

Informative!

Good detail on mitochondrial function and cellular energy production , without a biochemistry background this book is great to understand the core pincuplies of some key processes and in good step by step detail that many either books on nutrition just gloss over as if readers wouldn't be interested, wish there were more audible books like this .

10 people found this helpful

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  • J. Root
  • 17-09-2020

Mitochondria; Not just ATP energy generators...

If you're looking to build a house, you don't start building the roof. You start with the foundation, build the rest of the framework from the ground up. Same thing with the human body when it comes to health and wellness. Mitochondria are the foundation of health at a cellular level.

When Mitochondria function optimally, it means the rest of your body and it's metabolism is working as it should. When your metabolism is off, it impacts your Mitochondria and subsequently energy production and overall health and wellness. Its a cyclical relationship and one that we generally don't think of. We tend to think that the Mitochondria just handle their business as part of normal metabolic function.

Unfortunately that's not the case. There are so many factors that go into metabolic function that it would take an entire book to explain them all in detail. This is that book. If you're looking to optimize health, and understand that you build a strong house from the foundation up - this book is essential reading.

The great thing is you don't need a medical degree to understand it either. A basic level of biology, physics and anatomy and physiology is enough to really get a lot of value from this material.

7 people found this helpful

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  • Dreamweaver
  • 08-05-2020

Liberating!

Part of the Life Extension movement, understanding AGING as a disease, and not inevitable, explores scientific ways to add joy and power, to live up to 115-120 years. Why not? Read this along with Lifespan, by Dr David Sinclair, & The Switch, by Clements.

7 people found this helpful

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  • Lori
  • 12-10-2020

mostly good

This is pretty technical with a lot of vocabulary that is very specific to biology. For the average person you're left feeling like the recommendations for supplements are critical for survival. The book talks like it is an open and shut case. That was the one thing I did not like about the book. It seemed like some of the supplement recommendations didn't have a lot of scientific testing behind them. at least not on human beings. You don't know for sure about side effects from some of the supplements. That being said, the descriptions he gives about how the body operates are very eye-opening and interesting, technical jargon aside.

4 people found this helpful

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  • Amazon Customer
  • 12-03-2020

Great knowledge/ tough read

The book is on the next level and is hard to understand if you don't know a little to begin with. A significant book in the search for curing of diseases, part of the puzzle

4 people found this helpful

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  • Mark Fry
  • 26-07-2020

Highly Informative!

Thank you Dr Lee Know for writing this book! I finished listening to the audiobook and have purchased the paperback for further study. I also Listened to a few interviews you did promoting this book and learned even more.

3 people found this helpful

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  • Benjamin Wise
  • 19-05-2020

Very Insightful

I don't usually write book reviews but this book is exceptional. The science gets a little deep in places but not so much that it takes away from the book. A must read if your goal is understanding disease and aging.

3 people found this helpful

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  • Anonymous User
  • 22-12-2020

ineteresting audible

Enjoyed all the new information about Mitochondria very informative specially for beginners like me, now I know a lot about this tiny engine thank you

2 people found this helpful

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  • ecco
  • 04-09-2020

Die at a young age!

This is a fantastic and essential book for your library. It also contains crucial and fundamental insights into the role of CoQ 10 and PPQ's effect on enzymes that are responsible for mitochondrial health, repair and proliferation, aka youth and longevity.

2 people found this helpful

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  • mark frendo
  • 03-06-2020

Heavy going

I really paid close attention, but coming to it as a layman I really struggled to follow what was being said. ATCs, PPQs ETCs. It was all beyond me and difficult to pick up, learn and retain. Is that the fault of me or the book? I don’t know, but if you are having trouble sleeping, this may help.

6 people found this helpful

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    5 out of 5 stars
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  • Martin Lockyer
  • 19-02-2020

health: longevity and illness explained

plough through the first couple of chapters in spite of any lack of experience in biology that you might be concerned about. absolute gold dust. helping to connect the dots in a nee health paradigm.

4 people found this helpful

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  • Alastair
  • 12-05-2020

Hard work

20% interesting information, 80% in-depth biology and chemistry that was so far beyond my ability to comprehend it was essentially meaningless.

3 people found this helpful

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  • Scott
  • 31-08-2020

Highly Recommend!

Simply Fantastic! A magnitude of priceless information for health, longevity and fitness!

Will listen to it again!

2 people found this helpful

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  • Richard B
  • 04-02-2020

Absolutely Fascinating even for a layman

The first book I played twice since joining Audible, firstly because the content is quite complex but equally it puts a fascinatingly different perspective on common diseases, longevity, weight loss and more...

Thoroughly recommend for anyone interested in the next era of medical science!

2 people found this helpful

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