In this radiant and incisive debut novel in the tradition of works by ZZ Packer and Toni Cade Bambara, a Black woman fights to reclaim—and reinvent—her world after a little understood illness and a public health crisis threatens to upend everything she has.

Forty-seven-year-old Harmony Johnston is not suited for New York City life in 2019. From shampoos to synthetics to cell phones—the ubiquitous staples of modern daily life cause her physical pain, for reasons no one, including Harmony, understand. Doctors deny her illness is real, after seven years of enduring this private war, Harmony has her doubts too. Betrayed by her body and mind, as well as those closest to her—her obstinate physician sister, her sneaky best friend, and a spectral aunt who appears and disappears at whim—Harmony clings to the one doctor who offers hope.

In war, there are sacrifices: hair, boyfriend, sleep. Conditioned to place the comfort of others above her own needs, Harmony strives to be accommodating in an increasingly inhospitable world. But when the prestigious non-profit she works for relocates to an office with new wiring, painting, and carpeting (and the same old racial tensions) that exacerbate her pain, she quits her job and begins to set firm boundaries that upend her life, make her universe a little smaller, and magnify her loneliness.

As Harmony grows increasingly ill threatening her relationship with her one sympathetic doctor, she cuts herself off completely from the outside world and plunges into depression and literal darkness. When she eventually resurfaces, the world is irreversibly altered. With everyone now nearly as isolated as she is, Harmony resolves to re-connect with all she has lost. But can things ever really go back to normal?

At turns devastating, funny, and affirming, I Can Feel It All Over is an unforgettable debut novel about bodily autonomy, art, connection, and the pursuit of an authentic life amid the world's confines.