Noah Forman wakes up in a hospital and can't remember how he got there. He holds it together, taking comfort in the fact that the man he has loved since childhood is on the way. But when his one and only finally arrives, Noah is horrified to discover that he doesn't remember anything from the past three years. Clark Lehman built a life around the person who insisted from their first meeting that they were meant to be together.

When Eli Block steps into his parents' living room and sees his childhood crush sitting on the couch, he starts a shameless campaign to seduce the young rabbi. Unfortunately, Seth Cohen barely remembers Eli and he resolutely shuts down all his advances. As a tenuous and then binding friendship forms between the two men, Eli must find a way to move past his unrequited love while still keeping his best friend in his life. Not an easy feat when the same person occupies both roles.

The moment naïve, optimistic Jonathan Doyle glimpses a gorgeous blue-eyed stranger from afar, he believes in love at first sight. Unfortunately, he loses sight of the man before they meet and then spends years desperately trying to find him. Just as he is about to give up, Jonathan gets a break and finally encounters David Miller face to face.

After a passionate night together, Nate realizes Jake isn't as straight as he assumed, but he worries that what they shared was a fluke, a result of too much closeness for too long. For Jake, the question isn't how they ended up in bed together because he has always known that Nate holds his heart; it's how he'll convince Nate that he wants and needs to stay there.

Not even his mother's funeral can convince self-proclaimed party boy Zach Johnson to tone down his snark or think about settling down. He is who he is, and he refuses to change for anyone. When straight-laced, compassionate Aaron Paulson claims he's falling for him, Zach is certain Aaron sees him as another project, one more lost soul for the idealistic Aaron to save. But Zach doesn't need to be fixed, and he refuses to be with someone who sees him as broken.