Liverpool, 1855. Ada Houston is alone. Her grandfather has recently passed away, and her brother is missing, last seen working on the Liverpool docks. Everyone assumes him to be dead. But she will not give up hope. Ada's determined search takes her to the Crimea, where she joins the team of Florence Nightingale's nurses. She may have set off looking for her brother, but along the way Ada finds friends, romance and a new purpose in her own life in the most troubling and difficult of places.

Arriving back in her hometown after spending some time training at the Infirmary for Women in New York, Maud can't wait to put her newfound skills to the test. But in a city built and run by men she must work hard to be accepted. Whilst her nurse friends welcome her back with open arms, there are others who do not wish her well, including the spiteful Nancy Sellers. She will stop at nothing to sabotage Maud's life and soon turns her attention to those Maud holds most dear.  

1914. Evie Munro is a Scottish fisher girl, working the herring season from Wick to Great Yarmouth. For Evie, every day is the same - gutting fish at the docks, shoulder-to-shoulder with her friends, followed by fresh bread, a warm whiskey toddy and an early night. But when Germany declares war, everything changes. As her village begins to empty of young men, Evie's life is marked by a heartbreaking tragedy. Her happiness destroyed, she vows to join the war effort as an army nurse, caring for wounded soldiers on the imposing hospital ship Britannic.

England, 1941. After three nights of relentless bombing from German aircraft, trained nurse Jo Brooks is told to report to the basement theater of Mill Road Hospital. She goes with a heavy heart, not wanting to leave behind her best friend Moira, who is desperately soothing new mothers on the maternity ward. As Jo arrives safely underground, the ward takes a direct hit. 

1918, London. Twenty-year-old Emily Burdon has been training as a nurse at St. Marylebone Infirmary, learning on the job as she tends to patients from the crowded poorhouses that ring the hospital as well as wounded soldiers returning from the war. She pours her heart into her nursing while she waits for happier times - peace in Europe and the return of her childhood sweetheart, Lewis, from the Western Front. But when the deadly Spanish Flu arrives in London on the heels of the war, Emily’s faith and courage are put to the test. 

Three very different girls sign up as trainee nurses at a big London teaching hospital in 1934. Dora leaves her overcrowded, squalid working-class home for a better life. But has she got what it takes to keep up with other, better-educated girls? And will her hated stepfather ever let her go? Helen is born for the job; her brother is a doctor, her all-powerful mother a hospital trustee. But will Helen’s secret misery be her downfall? An aristocratic rebel, Millie’s carefree attitude will find her up in front of Matron again and again. Will she ever care enough to make a nurse? Or will she go back to the glamorous life she was born to?

When Nazis break down the front door of 18-year-old Trudi’s home and seize the Jewish couple hiding in her attic, she’s devastated, and is suddenly solely responsible for their two innocent children. The whispered rumours about the resistance are her only hope. A man called Frans and his cousin Piet risk their lives every day helping scared and abandoned Jewish children escape into the countryside. Under the cover of night, she races to beg for their help.

As war looms in Europe, 18-year-old Jane Shaw runs the household as an unpaid servant on a meagre budget. When tragedy strikes and she loses her beloved younger brother in suspicious circumstances, Jane takes a position in service looking after Ned, a troubled young boy. Here she meets dashing David Heron, Ned's Uncle and they form an immediate attachment until she is dismissed after being accused of stealing a piece of jewellery. Returning home, Jane and her sister, Melia, are soon orphaned and left at the mercy of their Aunt Alice.

West Yorkshire, 1901. When Eli Simmonite takes in a heavily pregnant woman fleeing from peril, he feels sure no good will come of it. After all, settled folk don't need much reason to take against the travellers, so having one seek safety amongst his people is unheard of. When danger comes knocking, they leave devastation in their wake. Eli is left with the baby girl and his orphaned grandson; a reminder of the offer of aid that cost him his family. With no kin but the adopted family who hold her responsible for their demise, Rosie is filled with questions of her past.

For months, Marianne’s resistance network has carried out courageous missions from a remote farmhouse in Southern Provence, aiding the Nazis’ downfall. But one fateful night, they are viciously ambushed as German soldiers storm in, scattering, capturing or killing every last person there. Mourning the loss of her friends, Marianne will need every ounce of courage to survive. Not only has her life as a secret agent been critically compromised, but her heart has been shattered. Because Jack, her darling fiancé and fellow spy, fled in the chaos–and is accused of being a traitor.

Following a humiliating experience involving the man she thought she’d marry, Iris Tredwick signs up to the Wrens in order to escape and - hopefully - find ‘the right sort’ of man to please her mother. After a bumpy start, Iris manages to befriend outspoken Mary and dreamer Sally as they are sent to their first posting - in Orkney. There she meets engineer Rob, whose flirtatious nature both charms and confounds straight-laced Iris. Much more appropriate for her is local doctor Stewart, if only she felt the same spark for him as she does for Rob.

Paris, 1943. German soldiers drag me out onto the cobbled street and push me toward the waiting truck. I force myself to face forward as tears stream down my cheeks. If I look back, they’ll know. I can’t let them find my baby girl....

Lady Joanna Harcourt and her daughter, Sarah, discover their life of luxury at Goodwill House is over. Because with Lord Harcourt away fighting, the Harcourt girls are facing financial ruin. Lady Joanna is terrified of losing their home, but for Sarah, this means her dreams of becoming a doctor are over. Headstrong Sarah isn’t one to quit! War or not, she’s determined to find a way to save her home and follow her dreams - whatever it takes.

Hampshire, 1913. Amidst the glitz and glamour of England’s High Society, Sarah Trenwith is more of a wallflower living in the shadow of her beautiful sister Marianne. But as the war approaches Sarah will have to step out of the place society and her family have assigned her if she’s to do her part and claim the love she always dreamed of from afar.

Jane’s parents think Eddie’s rebellious ways will lead their beloved daughter into trouble. They forbid her from seeing Eddie, telling Jane to get a proper job as a nurse. But Jane cannot stand the idea of life without the boy she loves and secretly continues to see Eddie. The day she finds out that Eddie has betrayed her, she is utterly distraught. Were her parents right all along?