Humans have long thought of their bodies and minds as separate spheres of existence. The body is physical. But the mind is mental; it perceives, remembers, believes, feels, and imagines. Although modern science has largely eliminated this mind-body dualism, people still tend to imagine their minds as separate from their physical being. Even in research, the notion of the "self" as somehow distinct from the rest of the organism persists. Joseph LeDoux argues that we have hit an epistemological wall—that ideas like the self are increasingly barriers to discovery and understanding.

Scientists are learning more and more about how brain activity controls behavior and how neural circuits weigh alternatives and initiate actions. As we probe ever deeper into the mechanics of decision making, many conclude that agency—or free will—is an illusion. In Free Agents, leading neuroscientist Kevin Mitchell presents a wealth of evidence to the contrary, arguing that we are not mere machines responding to physical forces but agents acting with purpose.

Tomasello assembles nearly three decades of experimental work with chimpanzees, bonobos, and human children to propose a new framework for psychological growth between birth and seven years of age. Becoming Human places human sociocultural activity within the framework of modern evolutionary theory and shows how biology creates the conditions under which culture does its work.

The Blind Spot goes where no science book goes, urging us to create a new scientific culture that views ourselves both as an expression of nature and as a source of nature's self-understanding, so that humanity can flourish in the new millennium.

Philosopher Alva Noë explores the inseparability of life, art, and philosophy, arguing that we have greatly underestimated what this entangled reality means for understanding human nature. Life supplies art with its raw materials, but art, Noë argues, remakes life by giving us resources to live differently. Our lives are permeated with the aesthetic. Indeed, human nature is an aesthetic phenomenon, and art is the truest way of understanding ourselves. All this suggests that human nature is not a natural phenomenon.