Two years ago, Noelle North’s then-fiancé left her waiting at the church on Christmas - her wedding day and birthday. Now, she knows she cannot endure another holiday season at home in Boston. At the urging of four women at the assisted-living community where she serves as health director, Noelle decides to rent Seashell Cottage on the Gulf Coast of Florida for the holidays. She meets Silas Bellingham, the cutest seven-year-old boy she’s ever seen, and his great-grandmother, Althea. 

When Sukie's husband shacks up with her Pilates instructor, her domestic drama becomes the talk of her small Georgia town. Friends from her married life prove fickle, and Sukie hides at home, terrified of encountering the town gossips at the grocery store. Betsy, Sukie's neighbor, invites her to join "Fat Fridays", a weekly gathering at a local café where the women order whatever they crave - no calories counted. Over sausage pizza and sage advice, Sukie gets a grip on her new life.

When Ann Rutherford's husband dumps her for the bimbo in his office, unfairly leaving her without a home or a job, she reluctantly joins forces with Rhonda DelMonte to convert Rhonda's Florida seaside estate into the small upscale hotel it once was. Ann, quiet and reserved, is no match for brash, bossy Rhonda, who left the family's New Jersey butcher business after she won the Florida lottery.

Ellie Weatherby and the four other grandmothers living at Sanderling Cove decide with only two great-grandchildren, it’s time to swing into action. They invite their grandchildren to spend the summer at the cove, hoping to encourage romance between them. Ellie invites all three of her granddaughters to take over the management of the Sanderling Cove Inn so that she and her bridegroom can spend the time traveling in Europe for their honeymoon.

Since adolescence, 58-year-old Beth has lived her life with blinkers on, repressing the memory of a teenage trauma. Her mother, Marian, took control of that situation, and of all else in their family life—and as much as she could in the small town of Miner's Ridge as well. Now Marian is dead, and Beth, unemployed and in the middle of a humiliating divorce, is living with her gentle-hearted father in the family home. Beth feels obliged to take over her mother's involvement in the local town hall committee.