The fossilized remains of a previously unclassified hominin species are discovered in the Altai Mountains, prompting teams of scientists from around the globe to converge upon this isolated region of Siberia in search of further evidence to corroborate the revolutionary theory that a third proto-human ancestor coexisted with Neanderthals and primitive Homo sapiens. What awaits them is anything but extinct.

A team of scientists unlocks the secret of the next phase of human evolution in the most unstable geological region on the planet... at the bottom of the sea in the Pacific Ring of Fire. When a massive earthquake rocks Oceania, generating a tsunami that decimates the surrounding islands and sinks the research vessel, a rescue team is dispatched... only to find that the majority of the crew had been slaughtered prior to the ship's foundering.

Arizona shares nearly four hundred miles of international border with Mexico, thirty-six of which are completely unfortified. On one side lies desperation; on the other, opportunity. Tens of thousands of undocumented aliens pass through these thirty-six miles every year, only to find one of the harshest and most inhospitable deserts on the planet waiting for them. Hundreds die walking, casualties of the merciless sun, their bodies never to be identified.

A young girl vanishes in broad daylight on her tenth birthday. Her father, FBI Special Agent Phil Preston of the Child Abduction Rapid Deployment Team, devotes his life to finding her and discovers a pattern in a recent string of abductions. Dr. Les Grant leads a group of graduate students into the Wyoming wilderness in search of an unidentified Native American medicine wheel photographed by an anonymous hiker. Instead, they stumble upon a macabre tableau of suffering.

This is the way the world ends. Not with a bang but a scream. In the remote mountains of Northern Alaska, Dr. Riley Middleton and her team of archeologists discover a burial site containing mummified remains dating to the last ice age. None of them notice the warning carved into the entrance or realize that the tomb had been deliberately sealed from the outside until they’ve already released a virus that turns ordinary people into murderous monsters. But there’s something even more terrifying inside...something ancient...something unspeakably evil.