124. SHBG: One Reason Why “Normal” Hormones Can Still Feel Off cover art

124. SHBG: One Reason Why “Normal” Hormones Can Still Feel Off

124. SHBG: One Reason Why “Normal” Hormones Can Still Feel Off

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What if one overlooked protein quietly shaped your hormones, cycles, and metabolic health? In this episode of Cycle Wisdom, Dr. Monica breaks down Sex Hormone Binding Globulin (SHBG)—what it is, why it matters for both women and men, and how low levels can drive acne, irregular cycles, ovulation issues, insulin resistance, and hormone imbalance. You’ll learn how SHBG affects free testosterone and estrogen, when to test it, and how a restorative approach can improve it by treating root causes like insulin resistance, thyroid dysfunction, and liver health—helping hormones finally align with how you feel.


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