Fisiología del Hambre (NEJM 2025)
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About this listen
The Physiology of Hunger (NEJM 2025)
- Esta revisión resume investigación básica y traslacional sobre los circuitos fisiológicos que regulan el hambre y la ingesta, integrando señales periféricas y centrales que modulan la conducta alimentaria.
- Describe cómo hormonas y péptidos gastrointestinales, adiposidad y vías neuroendocrinas interactúan con el cerebro para ajustar apetito, recompensa y saciedad en distintos estados nutricionales.
- Concluye que comprender estos mecanismos aclara por qué el control del apetito falla en condiciones como obesidad y orienta el desarrollo de intervenciones dirigidas a rutas específicas.
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