The plague raging through London in 1665 has emptied the city. The only people left are those too poor to flee or those who selflessly struggle to control the contagion and safeguard the capital's future. Amongst them, though, are those prepared to risk their health for money - those who sell dubious 'cures' and hawk food at wildly inflated prices. Also amongst them are those who hold in their hands the future of the city's most iconic building - St Paul's Cathedral.

Matthew Bartholomew, unorthodox but effective physician to Michaelhouse college in medieval Cambridge, is as worried as anyone about the pestilence that is ravaging Europe and seems to be approaching England. But he is distracted by the sudden and inexplicable death of the Master of Michaelhouse - a death the University authorities do not want investigated.

Hugh of Singleton, fourth son of a minor knight, has been educated as a clerk, usually a prelude to taking holy orders. However, feeling no certain calling despite a lively faith, he turns to the profession of surgeon, training in Paris and then hanging out his sign in Oxford. A local lord asks him to track the killer of a young woman whose bones have been found in the castle cesspit. She is identified as the impetuous missing daughter of a local blacksmith, and her young man, whom she had provoked very publicly, is in due course arrested and sentenced at the Oxford assizes.

This collection of recordings about Brother Cadfael—a Benedictine monk and amateur sleuth in the 12th century—are performed here by the ideal actor. Sir Derek Jacobi, who portrayed Cadfael in several television adaptations, captivates listeners with his renderings of Monk's Hood, Saint Peter's Fair, The Heretic's Apprentice, The Potter's Field, The Summer of the Danes, and Brother Cadfael's Penance.

London in the spring of 1665 is a city full of fear. There is plague in the stews of St Giles, the Dutch fleet is preparing to invade, and a banking crisis threatens to leave Charles II's government with no means of paying for the nation's defence. Amid the tension, Thomas Chaloner is ordered to investigate the murder of Dick Wheler, one of the few goldsmith-bankers to have survived the losses that have driven others to bankruptcy - or worse.