At a genetics lab where a revolutionary strain of corn is being developed, FBI Special Agent Jack Dawson's best friend and fellow agent is brutally murdered, his body torn apart. Jack is convinced that Naomi Perrault, a beautiful geneticist and suspected terrorist, is behind the murder. But when Jack is framed for setting off a bomb that devastates the FBI lab in Quantico, Naomi becomes Jack's only hope of survival.
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A year has passed since the Sutter Buttes incident. Jack Dawson and Naomi Perrault, having failed to find the elusive bag of lethal New Horizons seed, are fired and the secret agency established under President Curtis to study the harvesters is shut down. As the harsh controls on biotechnology and genetics research imposed under President Curtis are rescinded by the new President, Naomi is recruited by a self-made billionaire in the pharmaceuticals industry who wants her to continue her original work in developing a food-based delivery system for vaccines.
Jack Dawson awakens from the terrifying nightmare of the events in Bitter Harvest to find his world under siege. Millions of people have died while he's lain in a coma in a Norwegian hospital, and the threat of humanity's total annihilation looms closer with every passing day. As Jack and his companions face the enemy on the ground, brilliant geneticist Naomi Perrault is forced to strike a bargain with the devil as she races against time to develop a super-weapon that could win the war.