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Power, Sex, Suicide
- Mitochondria and the Meaning of Life
- Narrated by: Nigel Patterson
- Length: 15 hrs and 54 mins
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Publisher's Summary
Mitochondria are tiny structures located inside our cells that carry out the essential task of producing energy for the cell. They are found in all complex living things, and in that sense, they are fundamental for driving complex life on the planet. But there is much more to them than that.
Mitochondria have their own DNA, with their own small collection of genes, separate from those in the cell nucleus. It is thought that they were once bacteria living independent lives. Their enslavement within the larger cell was a turning point in the evolution of life, enabling the development of complex organisms and, closely related, the origin of two sexes. Unlike the DNA in the nucleus, mitochondrial DNA is passed down exclusively (or almost exclusively) via the female line. That's why it has been used by some researchers to trace human ancestry daughter-to-mother, to "Mitochondrial Eve".
Mitochondria give us important information about our evolutionary history. And that's not all. Mitochondrial genes mutate much faster than those in the nucleus because of the free radicals produced in their energy-generating role. This high mutation rate lies behind our ageing and certain congenital diseases. The latest research suggests that mitochondria play a key role in degenerative diseases such as cancer, through their involvement in precipitating cell suicide. Mitochondria, then, are pivotal in power, sex, and suicide.
In this fascinating and thought-provoking book, Nick Lane brings together the latest research findings in this exciting field to reveal how our growing understanding of mitochondria is shedding light on how complex life evolved, why sex arose (why don't we just bud?), and why we age and die. This understanding is of fundamental importance, both in understanding how we and all other complex life came to be, but also in order to be able to control our own illnesses, and delay our degeneration and death.
Critic Reviews
"Full of startling insights into the nature and evolution of life as we know it." (The Economist)
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- Anonymous User
- 02-05-2024
My favourite book to fall asleep to...
Don't take this the wrong way, but the topic matter is so fascinating yet dense, and the narrators voice perfectly monotonous - that this book became my sleeping pill.
And in doing so, I discover and re-discover my own cell biology! It has impacted how I view bacteria and viruses that I share my body with, treating them less like intruders and more like allies, sometimes misplaced.
It's like discovering the deep sea of our own biology.
Riveting stuff.
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- Anonymous User
- 10-03-2021
Fantastic
A must read for everyone, very well narrated by Nigel. Five stars all round
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- Karl Kleimeyer
- 24-03-2020
learnt a lot about life and all sorts of things
quite complex book for me and as it went on i started figuring out a lot of things and it got easier for me to figure things out.going to listen again cos i learnt so much
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1 person found this helpful